CD2 antibody (PE)

Catalog No. ABIN135084

Product Details anti-CD2 Antibody (PE)

Target: CD2

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Mouse CD2, Mr 45-58 kDa

Characteristics: Rat Anti-Mouse CD2-PE

Immunogen: Crude plasma membranes of ESb cells

Clone: 12-15

Isotype: IgG1

Application Details

Application Notes: Working Dilution:
FACS: 05 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Comment:

In vitro inhibition of CTL-mediated lysis, Induction of T cell unresponsiveness in vivo

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Buffer: Product is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS / NaN3 and a stabilizing agent.

Handling Advice: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Target Details for CD2

Target: CD2

Alternative Name: CD2 (CD2 Products)

Background: CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. It is expressed on the surface of > 95 % of thymocytes, and essentially all B cells, T cells and NK cells. In the mouse, CD2 is the receptor for CD48. CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling and intrathymic differentiation.5