PARK7/DJ1 antibody (N-Term)

Catalog No. ABIN121180

Product Details anti-PARK7/DJ1 Antibody

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Binding Specificity: AA 1-189, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PARK7/DJ1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Human Parkinson Disease Protein 7 (Park7/DJ-1). Other species not tested.

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human GST-DJ1 (1-189 aa) purified from E. coli

Clone: 1B11

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution for Western blot is 1:500 approx. 1:2,000 (starting dilution is 1:1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline, pH 7.4, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Can be stored at 2-8 °C for up to one month, but store at -20 °C for long term storage. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for PARK7/DJ1

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Alternative Name: DJ-1 / PARK7 (PARK7 Products)

Background: Park7/DJ-1, which is a small 189 amino acid protein, is a ubiquitously expressed protein involved in various cellular processes including spermatogenesis and fertilization, cancer, RNA-binding, androgen-receptor signaling and oxidative stress. Mutations in the Park7/DJ-1 are the cause of autosomal recessive early-onset Parkinson's disease 7 (Park7).Synonyms: Oncogene DJ1, Parkinson disease protein 7

UniProt: Q99497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport