CEBPB antibody (N-Term)

Catalog No. ABIN121153

Product Details anti-CEBPB Antibody

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Binding Specificity: AA 1-271, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human C/EBP-beta (1-271 aa) purified from E. coli

Clone: 47A1

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1/500 - 1/2,000), recommended starting dilution is 1:1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: CEBPB (CEBPB Products)

Background: CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPα, C/EBPβ, C/EBPδ, C/EBPε, and C/EBPγ. Among these proteins, C/EBPβ is usually highly expressed in liver, intestine, lung and adipose. C/EBPβ has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated.Synonyms: C/EBP beta, CCAAT/enhancer-binding protein beta, LAP, Liver activator protein, NF-IL6, Nuclear factor NF-IL6, TCF5, Transcription factor 5

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation