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Endoglin antibody

ENG Reactivity: Human WB, FACS, IP Host: Mouse Monoclonal MEM-226 unconjugated

Catalog No. ABIN120662

Datasheet as PDF

Target See all Endoglin (ENG) Antibodies

Endoglin (ENG)
Reactivity
162

63

42

17

10

6

5

3

3

3

1
Human
Host
101

85

16

1
Mouse
Compatible Secondaries
Clonality
103

99

1
Monoclonal
Conjugate
94

24

22

22

13

7

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Endoglin antibody is un-conjugated
Application
134

122

55

49

33

18

16

14

14

13

13

7

6

5

4

2

2

2

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Cross-Reactivity (Details)

Species reactivity (tested):Human

Purification

Protein-A affinity chromatography

Purity

> 95 % pure (by SDS-PAGE)

Immunogen

Recombinant Vaccinia Virus containing human CD105 cDNA

Clone

MEM-226

Isotype

IgG2a

Top Product

Discover our top product ENG Primary Antibody
anti-Endoglin (ENG) (AA 58-110) antibody
ENG Reactivity: Human, Mouse, Rat, Dog WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Endoglin (ENG) (AA 27-137) antibody
ENG Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Endoglin (ENG) (AA 26-136) antibody
ENG Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Endoglin (ENG) (AA 26-136) antibody
ENG Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG Reactivity: Human FACS, IHC, ELISA, ICC Host: Mouse Monoclonal 3A9 unconjugated

anti-Endoglin (ENG) (AA 27-226) antibody
ENG Reactivity: Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG Reactivity: Human, Rat WB, FACS, IP, CyTOF Host: Mouse Monoclonal MEM-226 unconjugated

anti-Endoglin (ENG) (AA 601-658) antibody
ENG Reactivity: Human, Rat ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Endoglin (ENG) antibody (APC)
ENG Reactivity: Human, Rat FACS Host: Mouse Monoclonal MEM-226 APC

anti-Endoglin (ENG) (AA 370-430) antibody
ENG Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

Fow Cytometry. Immunoprecipitation. Western blotting (non-reducing conditions only).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date

12 months
Target

Endoglin (ENG)

Alternative Name

CD105 / Endoglin (ENG Products)

Background

CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1

UniProt

P17813