Transferrin Receptor antibody
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- Target See all Transferrin Receptor (TFRC) Antibodies
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Transferrin Receptor antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity Chromatography on Protein A
- Immunogen
- KG1 human acute myelogenous leukaemia cell line
- Clone
- MEM-189
- Isotype
- IgG1
- Top Product
- Discover our top product TFRC Primary Antibody
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anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC Reactivity: Human FACS, IP, ICC Host: Mouse Monoclonal MEM-75 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 578-765) antibodyTFRC Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) antibodyTFRC Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 1-140) antibodyTFRC Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) antibody (Biotin)TFRC Reactivity: Human FACS, IP, ICC Host: Mouse Monoclonal MEM-75 Biotin
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 649-677), (C-Term) antibodyTFRC Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB20736 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 608-727) antibodyTFRC Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1A1B2 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) antibodyTFRC Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1E6 unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibodyTFRC Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibodyTFRC Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Flow cytometry: use 5 μL of neat antibody to label 10^6 cells Immunoprecipitation. Western Blotting (non reducing conditions).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- TBS buffer pH 8.0, 15 mM Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - Expiry Date
- 12 months
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Alternative Name
- CD71 / TFRC (TFRC Products)
- Background
- CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.Synonyms: TfR1, Transferrin receptor protein 1, p90
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
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