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Transferrin Receptor antibody (FITC)
TFRC
Reactivity: Rat
FACS
Host: Mouse
Monoclonal
OX-26
FITC
Product Details anti-Transferrin Receptor Antibody (FITC)
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Target
See all Transferrin Receptor (TFRC) Antibodies
Transferrin Receptor (TFRC)
(Transferrin Receptor (p90, CD71) (TFRC))
Reactivity
All reactivities for Transferrin Receptor antibodies
Rat
Host
All hosts for Transferrin Receptor antibodies
Mouse
Clonality
All clonalities for Transferrin Receptor antibodies
Monoclonal
Conjugate
All conjugates for Transferrin Receptor antibodies
This Transferrin Receptor antibody is conjugated to FITC
Application
All applications for Transferrin Receptor antibodies
Flow Cytometry (FACS)
Purification
Affinity chromatography on Protein G
Immunogen
PHA activated rat lymphocytes. Spleen cells from immunised Balb/c mice were fused with cells from the NS1 mouse myeloma cell line.
Clone
OX-26
Isotype
IgG2a
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Discover our top product TFRC Primary Antibody
Alternatives
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Application Details
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Application Notes
Flow cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Transferrin Receptor
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Target
Transferrin Receptor (TFRC)
(Transferrin Receptor (p90, CD71) (TFRC))
Alternative Name
CD71 / TFRC (TFRC Products )
Background
CD71 is a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimers, Parkinsons, Huntingtons and Multiple Sclerosis.Synonyms: TfR1, Transferrin receptor protein 1, p90
Gene ID
10116
UniProt
Q99376
Pathways
Transition Metal Ion Homeostasis
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