This antibody recognises human carcinoembryonic antigen. The antibody does not cross-react with normal cross-reacting antigen (NCA), or with biliary glycoprotein (BGP).
ELISA. Flow cytometry. Immunohistochemistry on frozen and paraffin embedded sections (1/1000, Requires protein digestion pre-treatment of Paraffin sections). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS buffer, pH 7.4 with 0.09 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Carcino Embryonic Antigen (CEA) is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100