CD38 antibody

Catalog No. ABIN118653

Product Details anti-CD38 Antibody

Target: CD38

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD38 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes a 45 kDa glycoprotein and has a reactivity pattern consistent with antibodies of the CD38 cluster.

Purification: Affinity Chromatography on Protein A.

Immunogen: Raised against NAMALWA Burkitt's lymphoma cell line of human origin.

Clone: AT13-5

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1/100, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation. Immunohistochemistry on frozen and paraffin embedded sections: 1/500 - 1/1000. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. 1 mM EDTA pH 8.0 is recommended for this purpose.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: TRIS buffered saline containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD38

Target: CD38

Abstract: CD38 Products

Synonyms: T10 antibody, Cd38-rs1 antibody, cd38 antibody, ADPRC 1 antibody, cADPr hydrolase 1 antibody, CD38 molecule antibody, CD38 antigen antibody, CD38 molecule L homeolog antibody, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 antibody, CD38 antibody, Cd38 antibody, cd38.L antibody

Background: CD38 is a type II integral membrane glycoprotein of 45 kDa which is present on early B and T cell libeages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes anf Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lymphocytes.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

Gene ID: 952

NCBI Accession: NP_001766

UniProt: P28907