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ITGAL antibody

Name: ITGAL antibody
SKU: ABIN118562
Price: 636 USD
Availability: InStock

ITGAL Reactivity: Human FACS, IP, IHC (fro) Host: Mouse Monoclonal 38 unconjugated

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD11 (ITGAL antibody)

FACS

1 image

Catalog No. ABIN118562

Datasheet as PDF

Target See all ITGAL Antibodies

ITGAL (Integrin alpha-L (ITGAL))
Reactivity
134

66

16

3

3

2

2

2

1

1

1

1
Human
Host
104

54

44

1
Mouse
Compatible Secondaries
Clonality
159

43

1
Monoclonal
Conjugate
75

27

23

18

7

6

6

4

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This ITGAL antibody is un-conjugated
Application
147

43

37

33

29

29

23

18

8

6

6

5

2

2

2

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

This antibody recognises the integrin alpha-L subunit, a 180 kDa glycoprotein expressed by all human leucocytes. The molecule is involved in cell-cell adhesion processes and binds to ICAM-1, 2 and 3.

Purification

Affinity Chromatography on Protein G.

Clone

38

Isotype

IgG2a

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ITGAL Reactivity: Human FACS, IP, IHC Host: Mouse Monoclonal 38 unconjugated

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ITGAL Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha-L (ITGAL) antibody
ITGAL Reactivity: Mouse FACS, IP, IHC (fro) Host: Rat Monoclonal M17-4 unconjugated

anti-Integrin alpha-L (ITGAL) antibody
ITGAL Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-25 unconjugated

anti-Integrin alpha-L (ITGAL) antibody
ITGAL Reactivity: Human FACS, IP, Func Host: Mouse Monoclonal MEM-25 unconjugated

anti-Integrin alpha-L (ITGAL) (AA 201-500) antibody
ITGAL Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha-L (ITGAL) antibody (Biotin)
ITGAL Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-25 Biotin

anti-Integrin alpha-L (ITGAL) antibody (PE)
ITGAL Reactivity: Human FACS Host: Mouse Monoclonal MEM-25 PE

Application Notes

Flow cytometry: Use 5 μL of 1/50-1/100 diluted antibody to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended positive control: Human Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

ITGAL (Integrin alpha-L (ITGAL))

Alternative Name

CD11a / ITGAL (ITGAL Products)

Background

CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain

Gene ID

3683

NCBI Accession

NP_002200

UniProt

P20701

Pathways

Activated T Cell Proliferation, Integrin Complex