CD11b antibody (PE)
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivity
- Human, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Purification
- Affinity Chromatography on Protein G
- Immunogen
- Rheumatoid synovial cells and human monocytes. Spleen cells from immunised BALB/c mice were fused with cells of the SP2 mouse myeloma cell line.
- Clone
- ICRF44
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAM Primary Antibody
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- Application Notes
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with distilled water.
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- This product is photosensitive and should be protected from light
- Storage
- 4 °C
- Storage Comment
- Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
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Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 3, pp. 559-61, (2006) (PubMed).
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Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 3, pp. 559-61, (2006) (PubMed).
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- CD11b (ITGAM Products)
- Background
- CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes. The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
- Gene ID
- 3684
- NCBI Accession
- NP_000623
- UniProt
- P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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