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L-Selectin antibody

SELL Reactivity: Chemical FACS Host: Mouse Monoclonal DREG unconjugated
Catalog No. ABIN1177376
  • Target See all L-Selectin (SELL) Antibodies
    L-Selectin (SELL) (Selectin L (SELL))
    Reactivity
    • 90
    • 70
    • 30
    • 18
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Chemical
    Host
    • 73
    • 57
    • 46
    • 1
    Mouse
    Clonality
    • 130
    • 43
    • 3
    Monoclonal
    Conjugate
    • 69
    • 26
    • 19
    • 13
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This L-Selectin antibody is un-conjugated
    Application
    • 133
    • 48
    • 48
    • 47
    • 26
    • 21
    • 18
    • 11
    • 11
    • 8
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Brand
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Clone
    DREG
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product SELL Primary Antibody
  • Application Notes
    This NA/LE format is useful for in vitro functional studies.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Kishimoto, Warnock, Jutila, Butcher, Lane, Anderson, Smith: "Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro." in: Blood, Vol. 78, Issue 3, pp. 805-11, (1991) (PubMed).

  • Target
    L-Selectin (SELL) (Selectin L (SELL))
    Alternative Name
    CD62L (L-selectin) (SELL Products)
    Target Type
    Chemical
    Background
    Reacts with a 76-95 kDa glycoprotein referred to as L-selectin or LECAM-1. CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. Dreg-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen sections of peripheral, but not mucosal lymphoid tissue. It thus defines L-selectin as a human lymphocyte homing receptor for peripheral lymph node HEV. This antibody is routinely tested by flow cytometric analysis.
    Synonyms: L-selectin
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