CD47 antibody
(2 references)-
- Target See all CD47 Antibodies
- CD47
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD47 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Brand
- BD Pharmingen™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Clone
- B6H12
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD47 Primary Antibody
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anti-CD47 (CD47) (AA 18-135) antibody
CD47 Reactivity: Human FACS, IF, IHC, ELISA, StM, Coat Host: Mouse Monoclonal CD47-3019 unconjugated
anti-CD47 (CD47) antibodyCD47 Reactivity: Human, Mouse FACS, IF, IHC, StM Host: Mouse Monoclonal B6H12-2 unconjugated
anti-CD47 (CD47) (AA 20-140) antibodyCD47 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-CD47 (CD47) (AA 18-219) antibodyCD47 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD47 (CD47) (AA 241-323) antibodyCD47 Reactivity: Mouse, Rat FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-CD47 (CD47) antibody (FITC)CD47 Reactivity: Human, Pig, Non-Human Primate FACS Host: Mouse Monoclonal MEM-122 FITC
anti-CD47 (CD47) (AA 18-135) antibodyCD47 Reactivity: Human FACS, WB, IF, IHC, ELISA, StM, Coat Host: Mouse Monoclonal CD47-2937 unconjugated
anti-CD47 (CD47) antibodyCD47 Reactivity: Human, Pig, Non-Human Primate FACS, WB, IHC (fro) Host: Mouse Monoclonal MEM-122 unconjugated
anti-CD47 (CD47) antibodyCD47 Reactivity: Human WB, IF, IHC, ELISA Host: Rabbit Monoclonal 4G11 unconjugated Recombinant Antibody
anti-CD47 (CD47) (AA 44-141) antibodyCD47 Reactivity: Human IF, IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Rh-related antigen CD47 is the signal-transducer integrin-associated protein." in: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).
: "Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2785-94, (1991) (PubMed).
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: "Rh-related antigen CD47 is the signal-transducer integrin-associated protein." in: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).
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- Target
- CD47
- Alternative Name
- CD47 (IAP) (CD47 Products)
- Background
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The B6H12 monoclonal antibody specifically binds to a 42-52 kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. The B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells.
Synonyms: IAP, CDw149, gp42, MER6, Neurophilin, OA3 , Rh-related antigen
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