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CD3 antibody

CD3 Reactivity: Human FACS, Func Host: Mouse Monoclonal HIT3a unconjugated
Catalog No. ABIN1177370
  • Target See all CD3 Antibodies
    CD3
    Reactivity
    • 183
    • 104
    • 26
    • 20
    • 17
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    Human
    Host
    • 218
    • 53
    • 20
    • 13
    • 9
    • 2
    Mouse
    Clonality
    • 303
    • 6
    • 1
    Monoclonal
    Conjugate
    • 96
    • 39
    • 32
    • 23
    • 23
    • 11
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD3 antibody is un-conjugated
    Application
    • 288
    • 82
    • 58
    • 52
    • 46
    • 37
    • 33
    • 23
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Brand
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Clone
    HIT3a
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD3 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Target
    CD3
    Alternative Name
    CD3 (CD3 Products)
    Background
    Reacts with the human epsilon-chain, a 20 kDa subunit of CD3/T cell antigen receptor complex found on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show this antibody to be mitogenic when used in conjuction with pokeweed mitogen. CD3 plays a role in signal transduction during antigen recognition. HIT3a antibody does not stain intracellular CD3 unlike the other CD3 clone, UCHT1.
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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