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CD25 antibody

Name: CD25 antibody
SKU: ABIN1177330
Availability: OutOfStock

IL2RA Reactivity: Human FACS, Func Host: Mouse Monoclonal M-A251 unconjugated

FACS

1 image

Catalog No. ABIN1177330

Datasheet as PDF

Target See all CD25 (IL2RA) Antibodies

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
Reactivity
168

117

36

10

10

5

3

2

2

2

1

1
Human
Host
138

83

80

2

2

1

1
Mouse
Compatible Secondaries
Clonality
231

70

4
Monoclonal
Conjugate
121

33

28

24

21

11

6

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD25 antibody is un-conjugated
Application
225

86

56

53

44

40

23

18

15

13

8

8

6

6

4

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Brand

BD Pharmingen™

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility

0.2 μm filtered

Endotoxin Level

Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone

M-A251

Isotype

IgG1 kappa

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Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative

Azide free

Storage

4 °C

Storage Comment

Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Target

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name

CD25 (IL2RA Products)

Background

Reacts with CD25, a 55 kDa glycoprotein known as the low-affinity interleukin-2 receptor (IL-2R). CD25 is expressed on activated lymphocytes (T and B) and monocytes, and associates with the p75 high-affinity receptor chain to form the IL-2R complex. The CD25 molecule reveals three epitope regions: A, B, and C. M-A251 antibody recognizes epitope region B. CD25 expression on lymphocytes is upregulated by anti-CD3 or PHA stimulation. Soluble IL-2R is produced following inflammatory responses. This antibody is routinely tested by flow cytometric analysis.
Synonyms: IL-2 Receptor alpha Chain

Pathways

JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation