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ICAM2 antibody
ICAM2
Reactivity: Mouse
FACS, IP, IHC (fro), BR, IHC (f)
Host: Rat
Monoclonal
3C4
unconjugated
Product Details anti-ICAM2 Antibody
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Target
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ICAM2
(Intercellular Adhesion Molecule 2 (ICAM2))
Reactivity
All reactivities for ICAM2 antibodies
Mouse
Host
All hosts for ICAM2 antibodies
Rat
Clonality
All clonalities for ICAM2 antibodies
Monoclonal
Conjugate
All conjugates for ICAM2 antibodies
This ICAM2 antibody is un-conjugated
Application
All applications for ICAM2 antibodies
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
Brand
BD Pharmingen™
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility
0.2 μm filtered
Endotoxin Level
Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Transfected Cell Line
Clone
3C4
Isotype
IgG2a kappa
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Discover our top product ICAM2 Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative
Azide free
Storage
4 °C
Storage Comment
Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
References for anti-ICAM2 antibody (ABIN1177303)
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Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos : "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness. " in: Immunity , Vol. 10 , Issue 1 , pp. 9-19 , (1999 ) (PubMed ).
Xu, Bickford, Luther, Carpenito, Takei, Springer : "Characterization of murine intercellular adhesion molecule-2. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 156 , Issue 12 , pp. 4909-14 , (1996 ) (PubMed ).
Target Details for ICAM2
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Target
ICAM2
(Intercellular Adhesion Molecule 2 (ICAM2))
Alternative Name
CD102 (ICAM2 Products )
Background
The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1. Synonyms: ICAM-2
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