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CD16 antibody

Name: CD16 antibody
SKU: ABIN1176930
Availability: OutOfStock

CD16 Reactivity: Human FACS Host: Mouse Monoclonal 3G8 unconjugated

FACS

1 image

(1 reference)

Catalog No. ABIN1176930

Datasheet as PDF

Target See all CD16 Antibodies

CD16
Reactivity
129

26

20

20

20

9

8

8

8

4

3

3

2

2

2

2

2

2

2

2

2

2
Human
Host
110

25

19

1
Mouse
Compatible Secondaries
Clonality
130

23

1
Monoclonal
Conjugate
60

18

14

13

7

5

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD16 antibody is un-conjugated
Application
127

34

26

26

25

24

21

15

6

5

5

3

3

2

2

1

1
Flow Cytometry (FACS)

Brand

BD Pharmingen™

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility

0.2 μm filtered

Endotoxin Level

Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

Human polymorphonuclear leukocytes

Clone

3G8

Isotype

IgG1 kappa

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anti-CD16 (CD16) antibody
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CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 Biotin

anti-CD16 (CD16) (AA 17-208) antibody
CD16 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 2G10A9 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated

anti-CD16 (CD16) antibody
CD16 Reactivity: Human FACS Host: Mouse Monoclonal GRM1 unconjugated

Restrictions

For Research Use only
Format

Liquid

Concentration

1.0 mg/mL

Buffer

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative

Azide free

Storage

4 °C

Storage Comment

Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Wirthmueller, Kurosaki, Murakami, Ravetch: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).
Target

CD16

Alternative Name

CD16 (CD16 Products)

Background

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcgammaRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
Synonyms: FcRIII, Fc-gamma RIII, FCG3, FCGR3, FCGRIII, FcgammaRIII, IGFR3

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process