CD11b antibody
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Brand
- BD Pharmingen™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Immunogen
- Human monocytes
- Clone
- ICRF44
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ITGAM Primary Antibody
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anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 145-340) antibodyITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 3A10H5 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3340 unconjugated
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- CD11b/Mac-1 (ITGAM Products)
- Background
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The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin beta2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
Synonyms: Mac-1alpha, integrin alphaM subunit, CR3 alpha chain - Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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