CD20 antibody (Cytoplasmic) (APC-H7)
(1 reference)-
- Target See all CD20 (MS4A1) Antibodies
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
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Binding Specificity
- Cytoplasmic
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD20 antibody is conjugated to APC-H7
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Application
- Intracellular Staining (ICS)
- Brand
- BD Phosflow™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- Human B lymphoma cell line
- Clone
- H1
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product MS4A1 Primary Antibody
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anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (C-Term) antibody
Verified MS4A1 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human FACS, WB, IHC, IF, StM Host: Mouse Monoclonal L26 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 213-297) antibodyMS4A1 Reactivity: Human FACS, WB, IHC, IF, ELISA, StM, Coat Host: Mouse Monoclonal MS4A1-3409 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human, Cow FACS, IP Host: Mouse Monoclonal MEM-97 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human, Cow FACS, IP Host: Mouse Monoclonal MEM-97 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) antibodyMS4A1 Reactivity: Human FACS, WB, IHC (p) Host: Mouse Polyclonal unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human FACS, IHC, IF, StM Host: Mouse Monoclonal rIGEL-773 unconjugated Recombinant Antibody
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human FACS Host: Mouse Monoclonal LT20 unconjugated
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibodyMS4A1 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro), ICC Host: Mouse Monoclonal 2H7 unconjugated
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- Comment
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BALB/c
- Sample Volume
- 5 μL
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with APC-H7 under optimum conditions, and unconjugated antibody and APC-H7 were removed.
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: "The biology of CD20 and its potential as a target for mAb therapy." in: Current directions in autoimmunity, Vol. 8, pp. 140-74, (2004) (PubMed).
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: "The biology of CD20 and its potential as a target for mAb therapy." in: Current directions in autoimmunity, Vol. 8, pp. 140-74, (2004) (PubMed).
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- Target
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- Alternative Name
- CD20 (MS4A1 Products)
- Synonyms
- B1 antibody, Bp35 antibody, CD20 antibody, CVID5 antibody, LEU-16 antibody, MS4A2 antibody, S7 antibody, AA960661 antibody, Cd20 antibody, Ly-44 antibody, Ms4a2 antibody, MS4A1 antibody, bp35 antibody, cd20 antibody, ms4a2 antibody, leu-16 antibody, ms4a4c antibody, cd20-like antibody, membrane spanning 4-domains A1 antibody, membrane-spanning 4-domains, subfamily A, member 1 antibody, B-lymphocyte antigen CD20 antibody, MS4A1 antibody, Ms4a1 antibody, ms4a1 antibody, LOC101694281 antibody
- Background
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The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.
Synonyms: MS4A1, membrane-spanning 4-domains subfamily A member 1, B1, Bp35, LEU-16
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