TGFA antibody

Catalog No. ABIN114031

Product Details anti-TGFA Antibody

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivity: Human, Rat, Cow

Host: Sheep

Clonality: Polyclonal

Conjugate: This TGFA antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody detects Transforming Growth Factor alpha. Does not react with EGF or TGF-beta.

Purification: Ion Exchange chromatography

Immunogen: Mature human recombinant TGF-alpha conjugated to KLH.

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 3.1 mg/mL

Buffer: Borate buffered saline, pH 8.4, 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Alternative Name: TGF-alpha (TGFA) (TGFA Products)

Background: TGF-alpha is a 50 amino acid EGF-related polypeptide expressed in a range of tissues, including skin, pancreas, liver, duodenum, salivary glands, urinary and respiratory systems, and the developing and mature central nervous system (CNS). TGF-alpha is produced by monocytes, keratinocytes and neuronal cells and stimulates the proliferation of a range of epidermal and epithelial cells, through binding to the epidermal growth factor receptor (EGFR). TGFalpha is mitogenic for multipotent neural progenitors and is involved in astrogliosis.Synonyms: EGF-like TGF, ETGF, TGF type 1, Transforming growth factor alpha

Gene ID: 7039

NCBI Accession: NP_001093161

UniProt: P01135

Pathways: NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway