HBsAg
Reactivity: Hepatitis B Virus (HBV)
ELISA, WB, IFA
Host: Goat
Polyclonal
unconjugated
Application Notes
Suitable for use in ELISA (as Detection antibody, use BM3315 for Capture), Western blotand rapid assay formats. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Reconstitute with Deionized water.
Buffer
PBS without preservatives.
Preservative
Without preservative
Precaution of Use
Do Not Add Sodium Azide.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
HBSAg (HBsAg)
(Hepatitis B Virus Surface Antigen (HBsAg))
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.Synonyms: HBV surface antigen, Hepatitis B Virus