VNN2 antibody

Catalog No. ABIN1109468

Product Details anti-VNN2 Antibody

Target: VNN2 (Vanin 2 (VNN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VNN2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificity: This antibody reacts with human GPI-80. Does not react with mouse or rat Neutrophil.

Purification: Protein A agarose

Immunogen: PMA activated human neutrophil

Clone: 3H9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for VNN2

Target: VNN2 (Vanin 2 (VNN2))

Alternative Name: Vanin-2 / FOAP-4 (VNN2 Products)

Background: The GPI-80 Molecule (80 kDa) recognized by this antibody (clone 3H9) was shown to be present on human neutrophils. When 3H9 was added with a neutrophil stimulant (fMLP), the inhibition of neutrophil adherence was observed after 60 minutes incubation. 3H9 enhanced not only fMLP-induced chemotaxis but random migration of neutrophil as well. Furthermore, 3H9 clearly discriminated neutrophils from both basophils and eosinophils derived from humans.Synonyms: Glycosylphosphatidyl inositol-anchored protein GPI-80, VNN2, Vascular non-inflammatory molecule 2

Gene ID: 8875

NCBI Accession: NP_001229279

UniProt: O95498