MGC82892 antibody, MGC146409 antibody, PIG3 antibody, tumor protein p53 inducible protein 3 antibody, tumor protein p53 inducible protein 3 S homeolog antibody, Tp53I3 antibody, quinone oxidoreductase PIG3 antibody, TP53I3 antibody, tp53i3.S antibody, tp53i3 antibody, tp53I3 antibody
Background
TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein