Rabies Virus antibody
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- Target See all Rabies Virus (RABV) products
- Rabies Virus (RABV)
- Reactivity
- Rabies Virus
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Rabies Virus antibody is un-conjugated
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Application
- Immunofluorescence (IF), Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
- Purification
- Ammonium Sulphate Fractionation
- Immunogen
- Purified virions of SAD-Vnukova strain followed by Pitman-Moore strain. Spleen cells from immunised Balb/c female mice were fused with cells of the NSO myeloma cell line.
- Clone
- Rab-50
- Isotype
- IgG2b
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- Application Notes
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ELISA. Immunofluorescence. Functional Assays. Does not work in Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Rabies Virus (RABV)
- Alternative Name
- Rabies Virus (RABV Products)
- Target Type
- Virus
- Background
- Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
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