CD96 antibody

Catalog No. ABIN1106624

Product Details anti-CD96 Antibody

Target: CD96

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD96 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Specificity: This Monoclonal antibody NK92.39 reacts with CD96, also known as T cell-activated increased late expression (Tactile).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Clone: NK92-39

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C.

Target Details for CD96

Target: CD96

Alternative Name: CD96 (CD96 Products)

Background: CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR or CD155). Furthermore CD96 stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. This means NK cells have due to the receptor CD96 a dual receptor system that recognizes nectins and nectin-like molecules on target cells and mediates NK cells adhesion and triggering of effector functions. As PVR is highly expressed in certain tumors, this receptor system may be critical for NK cell recognition of tumors.Synonyms: Cell surface antigen CD96, T cell-activated increased late expression protein, T-cell surface protein tactile, TACTILE

Gene ID: 10225

NCBI Accession: NP_005807

UniProt: P40200