CD1a antibody (FITC)

Catalog No. ABIN1106008

Product Details anti-CD1a Antibody (FITC)

Target: CD1a

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1a antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: This antibody recognizes the largest (49 kDa) of the three variants of the CD1 heavy chain, designated as CD1a. The 49 kDa polypeptide is associated with b2-microglobulin on human cortical thymocytes, dendritic cells and Langerhans' cells. It may also be expressed on some T cell leukemias and lymphoma. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, normal bone marrow mononuclear cells or normal tonsillar T and B lymphocytes.

Purification: Affinity chromatography

Clone: MCD1a

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.

Target Details for CD1a

Target: CD1a

Alternative Name: CD1a (CD1a Products)

Synonyms: CD1 antibody, FCB6 antibody, HTA1 antibody, R4 antibody, T6 antibody, CD1A antibody, CD1a molecule antibody, CD1 antigen antibody, T-cell surface glycoprotein CD1a antibody, CD1A antibody, CD1.1 antibody, LOC100156095 antibody, LOC101111409 antibody

Background: CD1a antigen is expressed on human cortical thymocytes, dendritic cells in peripheral lymph nodes and Langerhans' cells in normal, dysplastic and neoplastic tissue. CD1 has a domain organisation similar to that of MHC Class I and its expression is inversely correlated with that of TCR and MHC Class I.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen

Gene ID: 909

NCBI Accession: NP_001754

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process