CD51 antibody

Catalog No. ABIN1100650

Product Details anti-CD51 Antibody

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD51 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Specificity: Directed against the CD51 antigen, alpha chain of vitronectin receptor (VNR-a chain)which forms a complex with: CD61 antigen (GP IIIa or b3 chain), b5 Integrin and b1 Integrin.The platelet a-b3 complex functions as a vitronectin receptor and platelet adhesion to vitronectinis inhibited by this antibody.

Purification: Purified

Immunogen: cultured melanoma cells derived from a human melanoma metastasis

Clone: NKI-M9 (former PAF2a)

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: ITGAV/Integrin Alpha V/CD51 (ITGAV Products)

Background: Name/Gene ID: ITGAV
Family: Integrin

Synonyms: ITGAV, CD51, CD51 antigen, Integrin, alpha V, MSK8, Integrin Alpha V, Integrin alpha-V, VNRA, Vitronectin receptor, Integrin alphaVbeta3, VTNR

Gene ID: 3685

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex